歷史上充斥著無法解釋的奧秘和故事，從百慕達三角洲的失蹤案到失落的亞特蘭提斯城，大家對此已提出眾多猜疑，但卻很少有相對之答案。而隨著科學技術的進步，新的線索也會相繼出現嗎？「神秘探索」將努力用新的理論來破解歷史上存在最久的問題。採用「怪物探險之旅」中的必勝模式，每一集的「神秘探索」將在旅程中尋找一項神秘案件中的新線索。透過在僻處的考察，「神秘探索」的專家將結合他們的科學技術知識，以獨特的方式來檢查和分析物理證據。「神秘探索」不依賴檔案的資訊，而是去尋找答案，並用高科技的配件、相機和音頻分析來讓我們更接近真相水落石出的一刻。
History is rife with mysteries and stories of the unexplained -- from vanishings in the Bermuda Triangle to the lost city of Atlantis -- that have spawned plenty of speculation, but few answers. But with advances in science and technology, can new evidence be brought to light? MysteryQuest will endeavor to use these new theories to uncover the answers to history's most enduring questions. Employing the successful MonsterQuest format, each episode of MysteryQuest will feature a journey to find new clues about a single mystery. Through expeditions to remote locations, MysteryQuest experts will combine their knowledge of science and technology to look at each in a unique way, testing and analyzing the physical evidence. Instead of relying on archival footage, MysteryQuest goes on location to actively seek answers, deploying high-tech gadgetry, cameras, and audio analysis to bring us closer to the truth.
